Literature summary extracted from
Polydoridis, S.; Leonidas, D.D.; Oikonomakos, N.G.; Archontis, G.
Recognition of ribonuclease a by 3-5-pyrophosphate-linked dinucleotide inhibitors: a molecular dynamics/continuum electrostatics analysis (2007), Biophys. J., 92, 1659-1672.
Crystallization (Commentary)
EC Number |
Crystallization (Comment) |
Organism |
---|
4.6.1.18 |
multi-ns molecular dynamics simulations of enzyme in complex with inhibitor 5'-phospho-2'-deoxyuridine-3-pyrophosphate (P-5)-adenosine-3-phosphate. The adenylate 5'-beta-phosphate binding position and the adenosine syn orientation constitute robust structural features in the complex |
Bos taurus |
Inhibitors
EC Number |
Inhibitors |
Comment |
Organism |
Structure |
---|
4.6.1.18 |
5'-phospho-2'-deoxyuridine-3-diphosphate (P-5)-adenosine-3'-phosphate |
i.e. pdUppA-3'-p, multi-ns molecular dynamics simulations of enzyme in complex with inhibitor |
Bos taurus |
|
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
4.6.1.18 |
Bos taurus |
P61823 |
- |
- |